Changjing Wu | Natural Medicine | Best Researcher Award

Published on by China Scientist

Assoc. Prof. Dr. Changjing Wu | Natural Medicine | Best Researcher Award

Changjing Wu is an Associate Professor at the Institute of Translational Medicine, Zhoukou Normal University. He holds a doctoral degree in natural medicinal chemistry from Shenyang Pharmaceutical University and has previously worked in both industry and academia, including as an engineer at the Marine and Natural Medicine Research Center in Shandong. His research focuses on the discovery and pharmacological evaluation of bioactive natural compounds for the treatment of diabetes, obesity, neurodegenerative diseases, and aging-related conditions. He has published widely in international journals such as Molecules, Frontiers in Pharmacology, Scientific Reports, and Frontiers in Chemistry, and is credited with several national patents on novel therapeutic compounds. Wu is recognized for his expertise in natural product chemistry, translational medicine, and applied drug development.

Assoc. Prof. Dr. Changjing Wu | Zhoukou Normal University | China

Profiles

SCOPUS

ORCID

Education

  • Changjing Wu pursued his academic journey with a strong foundation in pharmaceutical sciences. He completed his undergraduate studies in pharmaceutical marketing at Shenyang Pharmaceutical University. He then advanced his expertise with a master’s degree in medicinal chemistry at the Academy of Military Medical Sciences of the Chinese People’s Liberation Army. Building on this foundation, he earned his doctoral degree in natural medicinal chemistry at Shenyang Pharmaceutical University, where he focused on the discovery and development of bioactive compounds from natural sources.

Experience

  • Changjing Wu has built a career that bridges both industry and academia. He began his professional path as an engineer at the Marine and Natural Medicine Research Center of Shandong International Biotechnology Park Development Co., Ltd., where he engaged in innovative drug discovery work. He then transitioned into academia at Zhoukou Normal University, Institute of Translational Medicine. Starting as a lecturer, he advanced to the role of associate professor, contributing to teaching, mentorship, and research leadership. His career reflects a consistent commitment to the exploration of bioactive natural products and their potential therapeutic applications.

Awards and Recognition

  • Wu has contributed significantly to the study of natural product chemistry, pharmacology, and translational medicine. He has served as co-corresponding author on multiple peer-reviewed publications in international journals, including Molecules, Frontiers in Pharmacology, Scientific Reports, Journal of Molecular Endocrinology, and Frontiers in Chemistry. His works include studies on benzofuran derivatives, sodium danshensu, jujube extracts, phytohemagglutinin, and aspulvinones, showcasing the therapeutic potential of natural products against conditions such as diabetes, obesity, and aging-related decline.

Skills and Expertise

  • Changjing Wu possesses strong expertise in natural medicinal chemistry, with skills in isolation, structural identification, and bioactivity evaluation of natural compounds. His research is complemented by abilities in collaborative teamwork, project development, and scientific communication. His role as both a co-first and co-corresponding author in major publications demonstrates his skills in both leadership and scientific writing. Additionally, his success in patent development underscores his applied research capability and translational outlook.

Research Focus 

  • Wu’s research primarily centers on the discovery, structural modification, and pharmacological evaluation of natural compounds with therapeutic potential. His focus areas include cholinesterase inhibitors for neurodegenerative diseases, modulators of muscle metabolism, natural compounds for obesity and diabetes management, and bioactive molecules that promote longevity and stress resistance. By integrating chemistry with pharmacology, his work aims to develop novel therapeutic candidates from natural sources for modern healthcare needs.

Publications

  • Mulberroside A: A Multi-Target Neuroprotective Agent in Alzheimer’s Disease via Cholinergic Restoration and PI3K/AKT Pathway Activation
    Authors: Jin Li; Jiawen Wang; Yaodong Li; Jingyi Guo; Ziliang Jin; Shourong Qiao; Yunxia Zhang; Guoyin Li; Huazhen Liu; Changjing Wu
    Journal: Biology
    Year: 2025

    Benzofuran Derivatives from Cortex Mori Radicis and Their Cholinesterase-Inhibitory Activity
    Authors: Xiang Cui; Zehong Huang; Shanshan Deng; Yunxia Zhang; Guoyin Li; Lining Wang; Yanru Deng; Changjing Wu
    Journal: Molecules
    Year: 2024

    Downregulation of NEDD4L by EGFR Signaling Promotes the Development of Lung Adenocarcinoma
    Authors: Guoyin Li; Zewen Song; Changjing Wu; XiaoYan Li; Liping Zhao; Binghua Tong; Zhenni Guo; Meiqing Sun; Jin Zhao; Huina Zhang et al.
    Journal: Journal of Translational Medicine
    Year: 2022

    Butenolide Derivatives from Aspergillus terreus Selectively Inhibit Butyrylcholinesterase
    Authors: Xiang Cui; Shanshan Deng; Guoyin Li; Yunxia Zhang; Lining Wang; Changjing Wu; Yanru Deng
    Journal: Frontiers in Chemistry
    Year: 2022

    Aspulvinones Suppress Postprandial Hyperglycemia as Potent α-Glucosidase Inhibitors From Aspergillus terreus ASM-1
    Authors: Changjing Wu; Xiang Cui; Luzhen Sun; Jiajia Lu; Feng Li; Minghui Song; Yunxia Zhang; Xinqi Hao; Congkui Tian; Maoping Song; Xiaomeng Liu
    Journal: Frontiers in Chemistry
    Year: 2021

Conclusion

  • Changjing Wu has cultivated a career that combines rigorous training, academic leadership, and applied scientific innovation. His contributions span from fundamental natural product research to translational applications with real-world impact in drug development. Through his publications, patents, and teaching, he has established himself as a dedicated researcher and educator in the field of natural medicinal chemistry and translational medicine.