Published on by China Scientist

Dr. Xiao Sheng | Drosophila | Young Scientist Award 

Sheng Xiao is a researcher at the Navy Medical University specializing in biochemistry and molecular biology. Her work bridges modern biomedical science with traditional Chinese medicine, focusing on aging, cancer development, and intestinal health. She has led projects exploring the molecular mechanisms of herbal compounds and their therapeutic potential, earning recognition such as the Outstanding Poster Award at an international biology congress and the title of “Shizhen” scholar. Actively involved in professional societies and editorial boards, she is recognized as an emerging leader dedicated to advancing innovative, interdisciplinary approaches to human health.

Dr. Xiao Sheng | Naval Medical University School of Pharmacy | China

Profiles

SCOPUS

ORCID

Education

  • Sheng Xiao pursued advanced studies in biochemistry and molecular biology, developing a strong foundation in both theoretical and applied biomedical sciences. Her academic journey has centered on understanding molecular mechanisms that connect human physiology with disease progression. By combining traditional Chinese medicine knowledge with modern molecular biology, she built expertise that enables her to study cellular pathways, signaling networks, and therapeutic interventions for complex health challenges such as aging, cancer, and intestinal disorders.

Experience

  • Sheng Xiao has gained extensive research experience through her leadership and participation in major projects. As a principal investigator, she has guided studies that examine the therapeutic role of Chinese herbal compounds in alleviating aging-related disorders through brain–gut communication and molecular signaling. She has also directed research on the role of nuclear lamina proteins in tumor progression, uncovering insights into mechanisms of cell competition. Beyond her leadership, she has contributed to national programs exploring the pharmacological basis of traditional medicinal plants and the regulation of intestinal stem cell differentiation. Her research career reflects both independent scientific leadership and collaborative excellence.

Awards and Recognition

  • Sheng Xiao’s scientific achievements have been recognized with several important honors. She received the Outstanding Poster Award at an international biology congress, which underscored the significance and clarity of her research contributions. Her innovative work in traditional Chinese medicine earned her recognition at a national forum on basic medical research, where her team achieved third prize in the medicine category. More recently, she was honored as a “Shizhen” scholar, a distinction that highlights her potential as a leader in integrating traditional and modern biomedical research. These recognitions demonstrate her impact within both national and international scientific arenas.

Skills and Expertise

  • Sheng Xiao possesses strong skills in molecular biology, biochemistry, and experimental design. She is adept at investigating signaling pathways that regulate disease progression, with expertise in areas such as cancer development, intestinal mucosal repair, and aging-related conditions. Her research skills include advanced laboratory experimentation, data analysis, and the integration of traditional medicine insights into modern biomedical frameworks. In addition to technical expertise, she has cultivated leadership, scientific writing, and project management abilities, reinforced by her service on editorial boards and professional committees.

Research Focus 

  • The central focus of Sheng Xiao’s research lies at the intersection of molecular biology, biochemistry, and traditional Chinese medicine. She is deeply interested in unraveling how natural compounds derived from herbs regulate cellular signaling pathways such as Keap–Nrf and srebp-mediated processes. Her work highlights the potential of combining ancient medicinal knowledge with cutting-edge molecular biology to address contemporary health challenges. By focusing on tumor biology, intestinal injury, and aging-related disorders, her research aims to translate mechanistic insights into innovative therapies that improve health outcomes.

Publications

  • Unlocking nature’s medicine cabinet through Drosophila–Driven exploration
    Authors: Xiao Sheng, Jianzheng He, Lei Zhang
    Journal: Phytomedicine

  • Werner syndrome exonuclease promotes gut regeneration and causes age-associated gut hyperplasia in Drosophila
    Authors: Kun Wu, Juanyu Zhou, Yiming Tang, Qiaoqiao Zhang, Lishou Xiong, Xiaorong Li, Zhangpeng Zhuo, Mei Luo, Yu Yuan, Xingzhu Liu, Xiao Sheng
    Journal: PLOS Biology

  • Phase separation of BuGZ regulates gut regeneration and aging through interaction with m6A regulators
    Authors: Qiaoqiao Zhang, Kai Deng, Mengyou Liu, Shengye Yang, Wei Xu, Tong Feng, Minwen Jie, Zhiming Liu, Xiao Sheng, Haiyang Chen
    Journal: Nature Communications

  • ClC‐c regulates the proliferation of intestinal stem cells via the EGFR signalling pathway in Drosophila
    Authors: Jinping Huang, Xiao Sheng, Zhangpeng Zhuo, Danqing Xiao, Kun Wu, Gang Wan, Haiyang Chen
    Journal: Cell Proliferation

  • Antioxidant Effects of Caffeic Acid Lead to Protection of Drosophila Intestinal Stem Cell Aging
    Authors: Xiao Sheng, Yuedan Zhu, Juanyu Zhou, La Yan, Gang Du, Zhiming Liu, Haiyang Chen
    Journal: Frontiers in Cell and Developmental Biology

Conclusion

  • Sheng Xiao represents an emerging leader in biomedical research who skillfully blends traditional medicine with modern molecular biology. Her leadership in important projects, recognition through awards, and active roles in professional organizations showcase her growing influence in the scientific community. With strong technical expertise, innovative vision, and dedication to improving human health, she continues to make meaningful contributions that bridge tradition and modern science in pursuit of transformative therapeutic strategies.

Xiao Sheng | Drosophila | Young Scientist Award

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