Zuoyun Wang | Biology | Best Researcher Award

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Dr. Zuoyun Wang | Biology | Best Researcher Award

Dr. Zuoyun Wang is a professor in the Department of Anatomy and Embryology at the School of Basic Medicine, Fudan University, and a doctoral supervisor. She obtained her PhD in Cell Biology from the Chinese Academy of Sciences. Her research focuses on the Hippo signaling pathway in tissue regeneration and tumorigenesis, using organoids, mouse models, and clinical samples. Dr. Wang has published over 30 papers in high-impact journals and has received multiple honors, including the Shanghai Oriental Talent award and the Excellent Youth Talent Award from the Chinese Academy of Sciences.

Dr. Zuoyun Wang | Fudan University | China

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Education

  • Dr. Zuoyun Wang earned her PhD in Cell Biology from the Institute of Biochemistry and Cell Biology at the Shanghai Institute for Biological Sciences, Chinese Academy of Sciences. Her academic training laid a solid foundation in the cellular and molecular mechanisms that regulate tissue development and disease processes.

Experience

  • Dr. Wang currently serves as a professor in the Department of Anatomy and Embryology at the School of Basic Medicine, Fudan University. She leads a dynamic research group and also serves as a doctoral supervisor, guiding the next generation of biomedical scientists. Her role includes both teaching and conducting cutting-edge research in cellular biology and tissue regeneration.

Awards and Recognition

  • Throughout her career, Dr. Wang has been recognized with numerous prestigious honors. These include the Shanghai Oriental Talent award, the Excellent Youth Talent Award and the Sanofi Excellent Youth Talent Award from the Chinese Academy of Sciences. She also received the Outstanding Youth Scholar Award from the Shanghai Society for Cell Biology and won first prize in the Shanghai University Teacher Innovation Competition, reflecting her excellence in both research and academic leadership.

Skills and Certifications

  • Dr. Wang possesses advanced expertise in molecular and cellular biology, particularly in relation to the Hippo signaling pathway. She is skilled in the use of organoids, genetically engineered mouse models, and the analysis of clinical tissue samples. Her approach integrates basic science and translational research, bridging the gap between laboratory findings and clinical applications.

Research Focus

  • The central focus of Dr. Wang’s research lies in the Hippo signaling pathway and its role in tissue regeneration and tumorigenesis. Her group investigates how this pathway contributes to maintaining tissue homeostasis and how its dysregulation may lead to disease. Using a combination of organoid cultures, animal models, and patient-derived samples, her work aims to uncover novel mechanisms and therapeutic targets for related diseases and cancers.

Conclusion

  • Dr. Zuoyun Wang is a leading biomedical scientist whose contributions have significantly advanced the understanding of tissue regeneration and cancer biology. Through her leadership, innovative research, and academic mentorship, she continues to influence the field of cell biology and provide valuable insights into disease diagnosis and therapy.

Publications

  • The Hippo Signaling Pathway Modulates Pancreatic Tissue Homeostasis
    Authors: Wang, X.; Du, J.; Li, H.; Cao, Z.; Cheng, Z.; Wang, Z.
    Journal: Cell Death Discovery

  • The Hippo Signalling Pathway in Bone Homeostasis: Under the Regulation of Mechanics and Aging
    Authors: Li, Z.; Lin, J.; Wu, J.; Suo, J.; Wang, Z.
    Journal: Cell Proliferation

  • DNA Bridging of FOXP3 Ladder-Like Multimer: Unveiling a Novel Transcriptional Regulation Paradigm
    Authors: Lu, Y.; Li, L.; Yang, H.; Li, B.; Wang, Z.
    Journal: The Innovation

  • MST1/2: Important Regulators of Hippo Pathway in Immune System Associated Diseases
    Authors: Zhou, J.; Li, L.; Wu, B.; Feng, Z.; Lu, Y.; Wang, Z.
    Journal: Cancer Letters

  • ASB3 Promotes Hepatocellular Carcinoma Progression by Mediating DR5 Ubiquitination in TRAIL Resistance
    Authors: Huang, L.; Che, Z.; Liu, F.; Ge, M.; Wu, Z.; Wu, L.; Chen, W.; Wang, Z.; Zhu, Z.; Xu, W. et al.
    Journal: The FASEB Journal

Prof. Jianzhong Zhu | Biological Sciences | Best Researcher Award | 1167

Published on by China Scientist

Prof. Jianzhong Zhu | Biological Sciences | Best Researcher Award

Prof. Jianzhong Zhu, Yangzhou University School of Veterinary Medicine, China

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📚 Early Academic Pursuits

Prof. Jianzhong Zhu embarked on his academic journey with a Ph.D. in Preventive Veterinary Medicine from Nanjing Agricultural University, which he completed in 2000. This solid foundation set the stage for his future research endeavors in the field of veterinary medicine.

💼 Professional Endeavors

Since earning his doctorate, Prof. Zhu has dedicated his career to exploring innate immune signaling pathways and the infection and immunity mechanisms of porcine viruses, specifically ASFV and PRRSV. His research has received funding from prestigious organizations such as the International Foundation of Science (IFS), NIH R01, the National Science Foundation of China (NSFC), and the National Key Research and Development Project.

🔬CONTRIBUTIONS AND RESEARCH FOCUS

  • Prof. Zhu has made significant contributions to understanding the innate immune signaling pathways in pigs and chickens, particularly focusing on the cGAS-STING signaling and the interrelationship between porcine RIG-I-like receptors (RLR). His research on the immune evasion mechanisms of ASFV and the immune defense against PRRSV has been groundbreaking. Additionally, he has investigated the signaling mechanisms of TLR8 in livestock and humans.

🌟Impact and Influence

  • With over 90 research papers published in high-profile journals such as Immunity, EMBO J, Cancer Res, J. Immunol, J. Biol Chem, and J. Virol, Prof. Zhu’s work has significantly impacted the field of veterinary immunology. His research findings have advanced the understanding of immune responses in livestock, contributing to the development of better disease control strategies.

📖 ACADEMIC CITES

Prof. Zhu’s work has garnered substantial recognition within the scientific community, evidenced by his Scopus citation index of 2600 and an H-index of 28. His contributions have not only advanced academic knowledge but also influenced practical applications in veterinary medicine.

🌍 LEGACY AND FUTURE CONTRIBUTIONS

Prof. Zhu’s legacy is marked by his pioneering research and significant advancements in the understanding of innate immune signaling and porcine virus immunity. His ongoing projects continue to explore critical aspects of immune responses and pathogen interactions. The patent for the porcine RIG-I specific monoclonal antibody highlights his innovative approach to tackling veterinary health issues. His future contributions are anticipated to further revolutionize veterinary immunology and enhance disease management in livestock.

📰PUBLICATIONS

      • Characterization of three African swine fever viruses from different clinical settings revealed a potential attenuation mechanism
        • Authors: Zhang, J., Wang, Y., Zhang, K., Li, R., Zhu, J.
        • Journal: Animal Diseases, 2024, 4(1), 24
      • Porcine TLR8 signaling and its anti-infection function are disturbed by immune checkpoint receptor TIM-3 via inhibition of P13K-AKT pathway
        • Authors: Zheng, W., Ao, D., Cao, Q., Chen, N., Zhu, J.
        • Journal: International Journal of Biological Macromolecules, 2024, 269, 132018
      • Development of visual detection of African swine fever virus using CRISPR/LwCas13a lateral flow strip based on structural protein gene D117L
        • Authors: Zhang, D., Jiang, S., Xia, N., Zheng, W., Zhu, J.
        • Journal: Veterinary Microbiology, 2024, 293, 110073
      • A chimeric porcine reproductive and respiratory syndrome virus 1 strain containing synthetic ORF2-6 genes can trigger T follicular helper cell and heterologous neutralizing antibody responses and confer enhanced cross-protection
        • Authors: Li, S., Qiu, M., Li, S., Lu, Y., Chen, N.
        • Journal: Veterinary Research, 2024, 55(1), pp. 28
      • Viral co-infections targeting the porcine respiratory system: Consequences and limits of the experimental systems | Les co-infections virales affectant le système respiratoire porcin: conséquences et limites des systèmes d’étude
        • Authors: Meurens, F., Zhu, J., Renois, F.
        • Journal: Virologie, 2024, 28(1), pp. 9–21