Xiang Li | Epigenetics | Best Researcher Award Posted on 28/09/202428/09/2024 by sciencefatherLeave a Comment on Xiang Li | Epigenetics | Best Researcher Award Prof. Xiang Li | Epigenetics |Best Researcher Award International Collaboration: His involvement in both national research grants in China and Australia, including the prestigious Early Career Researcher Grant from the Australian Academy of Science, underscores his global contribution to neuroscience research. Prof. Xiang Li, Wuhan University , China Profile Scopus OrcID Google Scholar 🏛️Early Academic Pursuits Xiang Li began his academic journey in the realm of epigenetics and cognitive neuroscience. His foundational work laid a strong focus on the neural and epigenetic mechanisms underlying memory, especially fear memory. Early in his career, he worked on deciphering the complex relationship between gene expression and cognitive function, laying the groundwork for his later breakthroughs in neurological research. 👨🔬 PROFESSIONAL ENDEAVORS As a Professor at Wuhan University, Xiang Li has built a distinguished career dedicated to unraveling the epigenetic and cognitive processes in fear memory. His groundbreaking research has led to significant advancements in understanding fear-related psychiatric disorders and developing targeted treatments. Notably, Li has successfully completed or is currently involved in projects such as Neuronepigenetics during the Fear Condition and Fear Extinction Learning, and Multimodal Single-Cell Profiling of Human and Mouse Prefrontal Neuron Subregions. 🧬 RESEARCH FOCUS Nucleic Acid Modifications in Cognitive Function – His research sheds light on how nucleic acid modifications affect cognitive functions, particularly memory. Epigenetic Regulation in Neurological and Cerebrovascular Diseases – Li focuses on circular DNA/RNA’s role in regulating neuroimmune responses and neurodevelopment. Whole-Genome Detection Technologies – Xiang Li has pioneered techniques in epigenetics, pushing forward new technologies to detect changes across the genome, particularly related to memory formation and psychiatric disorders. 🏆 CONTRIBUTIONS AND AWARDS Xiang Li’s contributions extend beyond his publications. His leadership in the field has been acknowledged with prestigious research grants in both Australia and China, including the Early Career Researcher Grant from the Australian Academy of Science. In 2019, he was honored with the Mark Rower Award from the Australian Neuroscience Society. Additionally, he has been selected for the Hubei Province “100 Talent Plan”, further recognizing his outstanding contributions to neuroscience. 📊 IMPACT AND INFLUENCE Professor Xiang Li’s work has gained widespread recognition in the academic world. His research publications have amassed an impressive 1,895 citations, with an h-index of 22 and an i10-index of 34. Over the past five years, he has published more than 20 papers in highly respected journals such as Nature Neuroscience, Biological Psychiatry, PNAS, and the Journal of Neuroscience, contributing a cumulative impact factor exceeding 120. Two of his papers have been selected by F1000 as must-read articles, further cementing his influence in the neuroscience community. 🏅ACADEMIC CITES His work is widely referenced by scholars in the fields of neuroscience and cognitive research. With nearly 1,900 citations and a high h-index, his contributions are shaping the current understanding of memory-related psychiatric disorders. His work is pivotal in advancing therapeutic strategies that target cognitive and fear memory disorders. 🚀 LEGACY AND FUTURE CONTRIBUTIONS Looking ahead, Xiang Li’s research will continue to play a key role in uncovering the mechanisms that link epigenetics with cognitive neuroscience. His future work promises to further explore epigenetic regulatory mechanisms in neuroimmune cells and their role in cognitive function. His ongoing projects on whole-genome detection technology will likely yield new insights into neurological diseases, pushing the frontiers of both clinical and theoretical neuroscience. 📰PUBLICATIONS Epigenetic mechanisms mediating vulnerability and resilience to psychiatric disorders Authors: KJ Dudley, X Li, MS Kobor, TE Kippin, TW Bredy Journal: Neuroscience & Biobehavioral Reviews 35 (7), 1544-1551 The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory Authors: Q Lin, W Wei, CM Coelho, X Li, D Baker-Andresen, K Dudley, VS Ratnu, … Journal: Nature Neuroscience 14 (9), 1115-1117 Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation Authors: X Li, W Wei, QY Zhao, J Widagdo, D Baker-Andresen, CR Flavell, … Journal: Proceedings of the National Academy of Sciences 111 (19), 7120-7125 Activation of BDNF signaling prevents the return of fear in female mice Authors: D Baker-Andresen, CR Flavell, X Li, TW Bredy Journal: Learning & Memory 20 (5), 237-240 p300/CBP-associated factor selectively regulates the extinction of conditioned fear Authors: W Wei, CM Coelho, X Li, R Marek, S Yan, S Anderson, D Meyers, … Journal: Journal of Neuroscience 32 (35), 11930-11941
Nucleic Acid Modifications in Cognitive Function – His research sheds light on how nucleic acid modifications affect cognitive functions, particularly memory. Epigenetic Regulation in Neurological and Cerebrovascular Diseases – Li focuses on circular DNA/RNA’s role in regulating neuroimmune responses and neurodevelopment. Whole-Genome Detection Technologies – Xiang Li has pioneered techniques in epigenetics, pushing forward new technologies to detect changes across the genome, particularly related to memory formation and psychiatric disorders.