Jinming Zhou | Medicinal Chemistry | Best Researcher Award Posted on 09/11/202409/11/2024 by sciencefatherLeave a Comment on Jinming Zhou | Medicinal Chemistry | Best Researcher Award Dr. Jinming Zhou | Medicinal Chemistry| Best Researcher Award Research and Grant Success: Dr. Zhou’s research has been consistently supported by prestigious National Natural Science Foundation (NCSF) grants, with four approvals to date. This grant success not only reflects the high quality and impact of his research but also indicates his capacity to conduct rigorous and relevant studies that address critical health challenges. Dr. Jinming Zhou, Zhejiang Normal University , China Profile Scopus OrcID 🌱EARLY ACADEMIC PURSUITS Dr. Zhou’s academic journey began at Beijing Normal University, where he earned his Bachelor of Science (B.S.) in 2000 and Master of Science (M.S.) in 2003. His passion for rational drug design led him to pursue a Ph.D. at the Shanghai Institute of Organic Chemistry, where he specialized in this field, establishing a strong foundation in medicinal chemistry. Postdoctoral training followed at McGill University in Canada, where he continued advancing in rational drug design and gained international research exposure. 💼 PROFESSIONAL ENDEAVORS In 2010, Dr. Zhou joined the Institute of Medicinal Biotechnology at the Chinese Academy of Medical Science as an Associate Professor. Demonstrating outstanding contributions in drug research, he achieved full professorship in 2017. His career took a new turn in 2018 when he accepted a professorship at Zhejiang Normal University, where he also became the Director of the Drug Development and Innovation Center. Dr. Zhou’s leadership at this center has been pivotal in establishing innovative practices and groundbreaking projects. 🔬CONTRIBUTIONS AND RESEARCH FOCUS Dr. Zhou’s research team is at the forefront of developing anti-viral and anti-cancer drugs. His group combines rational drug design and applied medicinal research to create effective therapeutic solutions. His work has a special emphasis on translational medicine, aiming to bridge scientific research and clinical applications. He has secured four prestigious National Natural Science Foundation (NCSF) grants, supporting his work in advancing therapeutic drug development. 📚ACADEMIC CITES With over a hundred publications, Dr. Zhou has significantly impacted medicinal chemistry, particularly in antiviral and anticancer drug design. His research has become a widely cited reference in related studies, underscoring his scientific contributions’ value and relevance. 🌍IMPACT AND INFLUENCE Dr. Zhou’s influence in the medicinal chemistry field is highlighted by his 100+ publications in high-impact journals, showcasing the scientific community’s recognition of his expertise. His achievements were honored in 2012 with the prestigious “Xiehe Star” award, recognizing his exceptional contributions to the field of drug design. 🌟LEGACY AND FUTURE AND CONTRIBUTIONS As Dr. Zhou continues his work at the Drug Development and Innovation Center, he is shaping a new generation of researchers focused on tackling global health challenges. His legacy is built not only on his published works but also on his mentorship and role in expanding the field of drug innovation. His ongoing research promises to further the understanding of rational drug design and its applications in combating complex diseases. 📄Publications “Inducing or enhancing protein-protein interaction to develop drugs: Molecular glues with various biological activity” Authors: Zhang, R., Zheng, Y., Xiang, F., Zhou, J. Journal: European Journal of Medicinal Chemistry, 2024, 277, 116756 “METTL3 inhibitor suppresses the progression of prostate cancer via IGFBP3/AKT pathway and synergizes with PARP inhibitor” Authors: Chen, X., Wang, M., Wang, H., Zhou, J., Wu, M. Journal: Biomedicine and Pharmacotherapy, 2024, 179, 117366 “Autophagy mediated targeting degradation, a promising strategy in drug development” Authors: Zhang, J., Pan, X., Ji, W., Zhou, J. Journal: Bioorganic Chemistry, 2024, 149, 107466 “A novel hydrophobic tag leads to the efficient degradation of programmed death-ligand 1” Authors: Gao, J., Xie, Y., Zhang, J., Cen, S., Zhou, J. Journal: RSC Medicinal Chemistry, 2024, 15(9), pp. 3038–3047 “Design and Synthesis of Dual-Target Inhibitors Targeting Androgen Receptors and Glucocorticoid Receptors to Overcome Antiandrogen Resistance in Castration-Resistant Prostate Cancer” Authors: Li, C., Han, X., Yan, Q., Wu, M., Zhou, J. Journal: Journal of Medicinal Chemistry, 2024, 67(5), pp. 3419–3436
Fang-Xin Wang | Organic Chemistry | Best Researcher Award Posted on 05/09/202409/09/2024 by sciencefatherLeave a Comment on Fang-Xin Wang | Organic Chemistry | Best Researcher Award Dr. Fang-Xin Wang | Organic Chemistry | Best Researcher Award Postdoctoral Research Experience: His postdoctoral research under the guidance of Prof. Yonggui Robin Chi at Nanyang Technological University provided him with international exposure and further honed his expertise. This experience contributes to his current research excellence and innovative approach. Dr. Fang-Xin Wang, Guangxi Normal University, China Profile Scopus OrcID 🎓Early Academic Pursuits Fang-Xin Wang (王芳昕) began his academic journey in chemistry at Lanzhou University, where he earned his Bachelor of Science (B.S.) degree in 2011. His academic focus deepened when he pursued a Ph.D. under the mentorship of Prof. Chun-An Fan, completing his degree in 2017. During this time, Wang developed a solid foundation in chemical research and gained valuable insights into organic chemistry and related fields. 👩🔬Professional Endeavors Upon completing his Ph.D., Fang-Xin Wang expanded his professional experience as a visiting scholar under Prof. Bin Tan at Southern University of Science and Technology. This brief yet significant experience further honed his research abilities. Subsequently, he moved to Singapore for a 4-year postdoctoral position with Prof. Yonggui Robin Chi at Nanyang Technological University. His time there allowed him to engage in high-level research and collaborate with renowned experts, fostering growth in both research methodologies and scientific understanding. In March 2022, he returned to China and began his independent academic career at Guangxi Normal University, specifically at the State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources. 🔬 CONTRIBUTIONS AND RESEARCH FOCUS Fang-Xin Wang’s research contributions are particularly significant in the areas of organic synthesis and medicinal chemistry. His primary focus areas include: Total Synthesis of Natural Products and Functional Molecules: He emphasizes synthesizing complex natural compounds and biologically active molecules that possess unique structural characteristics. His work aims to explore the pharmacological potential and functional applications of these molecules. Methodology Development: Wang is devoted to developing innovative synthetic methodologies that enhance the atom- and step-economy of chemical processes. His work in this area is aimed at streamlining chemical reactions and reducing waste, making organic synthesis more efficient and sustainable. 🌍Impact and Influence Through his academic endeavors, Fang-Xin Wang has made notable contributions to the fields of chemistry and medicinal resources. His research has the potential to influence drug discovery, with a particular emphasis on creating biologically relevant molecules that could serve as therapeutic agents. By improving synthetic methodologies, Wang has contributed to advancements in chemical processes that could be widely adopted in both academia and industry. 🏅ACADEMIC CITES AND RECOGNITION Although early in his independent academic career, Fang-Xin Wang’s research output has already gained attention. His publications and contributions are beginning to accumulate citations in leading scientific journals. These citations reflect the growing recognition of his work and its relevance to the broader scientific community. His contributions to both organic chemistry and natural product synthesis are likely to leave a lasting legacy in the field. 🌍FUTURE CONTRIBUTIONS As a young and dynamic researcher, Fang-Xin Wang is expected to continue making substantial contributions to his field. His future research may lead to breakthroughs in medicinal chemistry and the development of novel synthetic methodologies. His potential to shape the next generation of organic chemists and advance scientific knowledge is promising. Through his ongoing work at Guangxi Normal University, he will likely build a legacy as a pioneer in total synthesis and a leader in sustainable chemical processes. 📰PUBLICATIONS Total Synthesis of Quebrachamine and Kopsiyunnanine D Authors: Hui Liu, Wei Yuan, Meng-Yan Ran, Gang Wei, Yi Zhao, Zhi-Qiang Liao, Hong Liang, Zhen-Feng Chen, Fang-Xin Wang Journal: The Journal of Organic Chemistry Divergent Syntheses of (−)-Carvone-Derived Dimers Authors: Jia-Jia Liu, Bao-Qi Zhang, Kun She, Jiao Ran, Hui-Fang Li, Heng-Shan Wang, Fang-Xin Wang Journal: Tetrahedron Design and Synthesis of Novel Indole Ethylamine Derivatives as a Lipid Metabolism Regulator Targeting PPARα/CPT1 in AML12 Cells Authors: Yu-Chen Liu, Gang Wei, Zhi-Qiang Liao, Fang-Xin Wang, Chunxiao Zong, Jiannan Qiu, Yifei Le, Zhi-Ling Yu, Seo Young Yang, Heng-Shan Wang, et al. Journal: Molecules Assembly of Multicyclic Isoquinoline Scaffolds from Pyridines: Formal Total Synthesis of Fredericamycin A Authors: Fang-Xin Wang, Jia-Lei Yan, Zhixin Liu, Tingshun Zhu, Yingguo Liu, Shi-Chao Ren, Wen-Xin Lv, Zhichao Jin, Yonggui Robin Chi Journal: Chemical Science Carbene-Catalyzed Alkylation of Carboxylic Esters via Direct Photoexcitation of Acyl Azolium Intermediates Authors: Shi-Chao Ren, Wen-Xin Lv, Xing Yang, Jia-Lei Yan, Jun Xu, Fang-Xin Wang, Lin Hao, Huifang Chai, Zhichao Jin, Yonggui Robin Chi Journal: ACS Catalysis
Fang-Xin Wang’s research contributions are particularly significant in the areas of organic synthesis and medicinal chemistry. His primary focus areas include: Total Synthesis of Natural Products and Functional Molecules: He emphasizes synthesizing complex natural compounds and biologically active molecules that possess unique structural characteristics. His work aims to explore the pharmacological potential and functional applications of these molecules. Methodology Development: Wang is devoted to developing innovative synthetic methodologies that enhance the atom- and step-economy of chemical processes. His work in this area is aimed at streamlining chemical reactions and reducing waste, making organic synthesis more efficient and sustainable.