Dr. Xinyue Ren | Remyelination | Best Researcher Award
Xinyue Ren is a PhD candidate at the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, specializing in myelin regeneration. She has published five SCI-indexed journal papers and contributed to two patents, with her research focusing on DNA methylation and demethylation in promoting oligodendrocyte differentiation. Her groundbreaking work on the synergistic effects of Vitamin C and MEK inhibitor PD0325901 suggests promising therapeutic approaches for demyelination diseases. Xinyue has participated in three major research projects and received the prestigious Chinese Academy of Sciences Scholarship for College Students, highlighting her excellence in scientific innovation.
Dr. Xinyue Ren | Shanghai Institute of Materia Medical, Chinese Academy of Sciences | China
Profile
π Education
- Xinyue Ren is currently pursuing a PhD at the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, focusing on myelin regeneration. Her academic journey reflects a strong commitment to scientific excellence and innovation.
πΌ Experience
- As a dedicated researcher, Xinyue has contributed significantly to the field of epigenetics and neuroscience. She has been involved in three research projects, demonstrating her ability to lead and collaborate effectively. Her work has culminated in the publication of five SCI-indexed journal articles, either as the first author or a major participant.
π Honors and Awards
- Xinyue Ren has been recognized for her academic achievements with the prestigious Scholarship for College Students awarded by the Chinese Academy of Sciences, highlighting her exceptional contributions and potential in scientific research.
π οΈ Skills and Certifications
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Xinyue possesses expertise in epigenetic regulation, particularly DNA methylation and demethylation mechanisms. She is proficient in studying gene expression, cell differentiation, and the therapeutic potential of small molecules in neurological diseases.
π¬ Research Focus
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Her research centers on the interplay between DNA methylation and demethylation in regulating oligodendrocyte progenitor cell differentiation. She has uncovered groundbreaking findings on how Vitamin C and the MEK inhibitor PD0325901 synergistically induce DNA demethylation through hydroxy-methylation, promoting the differentiation of OPCs into OLs. These insights pave the way for potential combination therapies for demyelination diseases, a promising frontier in regenerative medicine.
Conclusion
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Based on her exceptional academic achievements, innovative findings in epigenetic regulation, and her contributions to potential therapeutic strategies, Xinyue Ren is highly suitable for the Best Researcher Award. Her work demonstrates excellence in scientific inquiry, innovation, and translational potential, making her a leading candidate for this recognition.
πPublications
- Trametinib, an anti-tumor drug, promotes oligodendrocytes generation and myelin formation
Authors: Yang, Y., Suo, N., Cui, S.-H., β¦ Guo, R., Xie, X.
Journal: Acta Pharmacologica Sinica, 2024, 45(12), pp. 2527β2539 - In situ reprogramming of cardiac fibroblasts into cardiomyocytes in mouse heart with chemicals
Authors: Chen, Z.-Y., Ji, S.-J., Huang, C.-W., β¦ Guo, R., Xie, X.
Journal: Acta Pharmacologica Sinica, 2024, 45(11), pp. 2290β2299 - The Aurora Kinase Inhibitor CYC116 Promotes the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells
Authors: Ji, S., Tu, W., Huang, C., β¦ Chen, Y., Xie, X.
Journal: Molecules and Cells, 2022, 45(12), pp. 923β934