Tongguo Shi | Cancer | Best Researcher Award

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Dr. Tongguo Shi | Cancer | Best Researcher Award

Tongguo Shi is an Associate Researcher at the First Affiliated Hospital of Soochow University, specializing in cancer immunology and molecular medicine. He earned his PhD from Nanjing University in 2016 and has since focused on tumor immune evasion, immune checkpoint regulation, and colorectal cancer research. His work has been published in leading journals such as Cancer Immunology, Immunotherapy and Cell Death & Disease, with multiple studies highlighting novel therapeutic targets. With expertise in molecular biology and immunological assays, he is dedicated to advancing cancer immunotherapy and precision medicine.

Dr. Tongguo Shi | The First Affiliated Hospital of Soochow University | China

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🎓Education

  • Tongguo Shi earned his PhD from Nanjing University in 2016, following his undergraduate studies at Liyi University, where he obtained a BA in 2010. His academic journey has equipped him with a strong foundation in medical and biological research, particularly in immunology and oncology.

👨‍🏫Experience

  • Currently serving as an Associate Researcher at the First Affiliated Hospital of Soochow University, Tongguo Shi has been contributing to medical research since December 2021. Prior to this role, he worked as a Research Associate at the same institution from 2017 to 2021, where he gained extensive experience in cancer immunology and molecular medicine. He also served as a Research Associate at the Center of Systems Medicine, Chinese Academy of Medical Sciences, from 2016 to 2017, further strengthening his expertise in cellular and molecular research.

🏆Awards and Recognitions

  • Throughout his career, Tongguo Shi has established himself as a leading researcher, contributing significantly to cancer immunotherapy and colorectal cancer studies. His role as a corresponding author in multiple high-impact journal publications highlights his expertise and recognition in the scientific community. His work on immunological mechanisms in cancer and inflammatory diseases has been widely cited, demonstrating the impact of his research.

💡Skills and Certifications

  • Tongguo Shi specializes in immuno-oncology, with a focus on tumor microenvironments, immune evasion mechanisms, and cancer immunotherapy. His research has explored the role of immune checkpoints such as B7-H3 and Tim-3 in colorectal and gastric cancers, as well as the impact of microRNAs on immune regulation in inflammatory diseases. His skills include molecular biology techniques, immunological assays, cancer cell signaling analysis, and translational research aimed at developing novel therapeutic strategies.

🔬 Research Focus

  • His research has led to groundbreaking findings on the interactions between immune cells and cancer cells, with a particular emphasis on T cell-mediated immune responses. He has published extensively in prestigious journals such as Cancer Immunology, Immunotherapy, Cell Death & Disease, Mucosal Immunology, and Gut, further advancing the understanding of cancer immunology and potential therapeutic interventions.

🌎Conclusion

  • Dr. Tongguo Shi exemplifies scientific excellence and collaborative leadership in cancer research. His work has significantly advanced the understanding of tumor immunology, cancer metabolism, and immunotherapy through high-impact interdisciplinary collaborations. His strong publication record, mentorship, and institutional partnerships highlight his commitment to groundbreaking discoveries that benefit both scientific progress and patient outcomes.

📖Publications

  • Elevated SPARC Disrupts the Intestinal Barrier Integrity in Crohn’s Disease by Interacting with OTUD4 and Activating the MYD88/NF‐κB Pathway
    Authors: J. Wang, Jiayu; Y. He, Yuxin; X. Zhu, Xingchao; J. Zhu, Jinghan; Z. Deng, Zilin; H. Zhang, Huan; Y. Chen, Yanjun; G. Zhang, Guangbo; T. Shi, Tongguo; W. Chen, Weichang
    Journal: Advanced Science, 2025

  • FASN Promotes Lipid Metabolism and Progression in Colorectal Cancer via the SP1/PLA2G4B Axis
    Authors: X. Liu, Xin; J. Lu, Jiachun; X. Ni, Xiangyu; Y. He, Yuxin; J. Wang, Jiayu; Z. Deng, Zilin; G. Zhang, Guangbo; T. Shi, Tongguo; W. Chen, Weichang
    Journal: Cell Death Discovery, 2025

  • Exploring the Link Between Noncoding RNAs and Glycolysis in Colorectal Cancer
    Authors: L. Xu, Liang; Y. Shen, Yu; C. Zhang, Chuanqiang; T. Shi, Tongguo; X. Sheng, Xuejuan
    Journal: Journal of Cellular and Molecular Medicine, 2025

  • The m6A Revolution: Transforming Tumor Immunity and Enhancing Immunotherapy Outcomes
    Authors: T. Shi, Tongguo; H. Zhang, Huan; Y. Chen, Yueqiu
    Journal: Cell & Bioscience, 2025

  • Exosome-Derived Proteins in Gastric Cancer Progression, Drug Resistance, and Immune Response
    Authors: J. Wang, Jiayu; H. Zhang, Huan; J. Li, Juntao; X. Ni, Xiangyu; W. Yan, Wenying; Y. Chen, Yueqiu; T. Shi, Tongguo
    Journal: Cellular & Molecular Biology Letters, 2024

Ben Wang | Oncology | Best Researcher Award

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Prof . Ben Wang | Oncology | Best Researcher Award

Recognition and Awards:
  •  Dr. Wang has received numerous awards throughout his career, including recognition from the National Science Foundation and various engineering societies. These accolades highlight his consistent contributions to advancing material science.
 Prof. Ben Wang , Zhejiang University , China

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🎓Early Academic Pursuits

  • Dr. Wang Ben was born in June 1983 in Qufu, China. His academic journey began with a Bachelor of Science in Chemical Engineering at Qufu Normal University in 2004. He then pursued his Master’s in Biology at Zhejiang University, focusing on the secondary metabolism of endophytic fungi from antitumor plants. His academic excellence earned him a Ph.D. in Chemistry & Biomedical Engineering from Zhejiang University in collaboration with Harvard University in 2011, under the guidance of Prof. Ruikang Tang and Prof. Ali Khademhosseini. His doctoral research focused on cellular shellization and surface engineering for single-cell modification and protection.

💼Professional Endeavors

  • Dr. Wang Ben’s career has been defined by his contributions to cancer metabolism and biomedical engineering. After completing his postdoctoral work at Zhejiang University in 2013, he served as an Associate Professor and Qiushi Young Scholar until 2022, when he was promoted to Professor. His work as Dean Assistant at the Institute of Translational Medicine and Deputy Director of the Zhejiang Key Laboratory of Frontier Medical Research on Cancer Metabolism showcases his leadership and contributions to the academic community. He also serves as a PI at the Cancer Institute of The Second Affiliated Hospital of Zhejiang University.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS

  • Dr. Wang’s research primarily revolves around cancer metabolism, cellular engineering, and biomedical innovations. His innovative research in translational medicine seeks to bridge laboratory research with practical clinical applications. Key areas of his research include:
    • Surface engineering for single-cell modification
    • Metabolism-related cancer research
    • Advancements in transvascular implantation devices

    Dr. Wang has also played a critical role as a panel judge for the National Natural Science Foundation of China and has been actively involved in several international research collaborations, contributing to a wide range of scientific publications.

🌍Impact and Influence

  • Dr. Wang’s impact extends beyond research, with significant contributions to education and mentorship. He has undertaken extensive teaching responsibilities, from undergraduate biology courses to graduate thesis guidance, impacting hundreds of students. His mentorship has produced many successful Ph.D. and master’s candidates who have gone on to establish themselves in academia and industry.As a journal reviewer for numerous prestigious scientific publications, including ACS Nano, Advanced Materials, and Biomaterials, Dr. Wang has helped shape the discourse in chemistry, biology, and biomedical engineering fields. His expertise is highly sought after by journals such as Chemical Science and Journal of Controlled Release.

🏅ACADEMIC CITES 

  • Dr. Wang Ben’s research is widely recognized within the academic community, reflected in his growing number of citations. His Google Scholar profile shows a robust citation record, underscoring the influence of his research in both cancer metabolism and biomedical engineering fields.

 📚LEGACY AND FUTURE CONTRIBUTIONS

  • Dr. Wang’s legacy in the field of cancer metabolism and transvascular implantation devices continues to grow. His future work promises to contribute further to cancer treatment, aiming to integrate innovative biomedical solutions into mainstream healthcare. His leadership roles and international collaborations highlight his dedication to driving forward impactful translational medical research.

📰PUBLICATIONS

  • Acid-base transformative HADLA micelles alleviate colitis by restoring adaptive immunity and gut microbiome
    • Authors: Cheng, W.; Zhou, X.; Jin, C.; Ji, F.; Wang, B.
    • Journal: Journal of Controlled Release, 2023, Volume 364, Pages 283–296.
  • Targeted glycan degradation potentiates cellular immunotherapy for solid tumors
    • Authors: Wu, J.; Wang, X.; Huang, Y.; Zhang, J.; Wang, B.
    • Journal: Proceedings of the National Academy of Sciences of the United States of America, 2023, Volume 120(38), Article e2300366120.
  •  A GSTP1-mediated lactic acid signaling promotes tumorigenesis through the PPP oxidative branch
    • Authors: Sun, Y.; He, Q.; Li, J.; Luo, H.; Luo, Y.
    • Journal: Cell Death and Disease, 2023, Volume 14(7), Article 463.
  •  Renal tubule-targeted dexrazoxane suppresses ferroptosis in acute kidney injury by inhibiting ACMSD
    • Authors: Zhang, Y.; Wu, J.; An, Q.; Wang, B.; Lin, W.
    • Journal: Nano Research, 2023, Volume 16(7), Pages 9701–9714.
  • Chemoimmunological Cascade Cancer Therapy Using Fluorine Assembly Nanomedicine
    • Authors: Zhang, Q.; Wu, P.; Wu, J.; Wang, S.; Wang, B.
    • Journal: ACS Nano, 2023, Volume 17(8), Pages 7498–7510.