Assoc Prof Dr . Guo Li | RNA Editing | Best Researcher Award

Innovative Research Techniques:
  • Innovative Research Techniques: Guo’s expertise in high-throughput screening techniques allows for the rapid identification of functional genes, a critical process in understanding genetic diseases and developing targeted therapies. His proficiency in both coding and non-coding gene functions is crucial for advancing our understanding of gene regulation.
Assoc Prof Dr . Shen Hu ,Xianghu Laboratory, China

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🎓Early Academic Pursuits

  • Dr. Guo Li began his academic journey with a strong focus on molecular biology and genetics. His early research laid the groundwork for advanced studies in genome editing, leading to a profound understanding of genetic mechanisms and innovations.

đź’ĽProfessional Endeavors

  • Over the years, Dr. Li has held various prestigious positions in academic and research institutions. His work primarily revolves around genome and RNA editing, employing cutting-edge technologies to address complex biological questions. His leadership in several projects has contributed significantly to advancements in genetic research.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS

  • Dr. Li’s research is characterized by three main pillars:
    1. GENOME AND RNA EDITING: He focuses on innovative methods for precise editing, enhancing our understanding of gene function and regulation.
    2. HIGH-THROUGHPUT SCREENING OF FUNCTIONAL GENES AND NON-CODING GENES: This work aims to identify and analyze gene functions at a large scale, providing insights into the roles of non-coding regions in gene expression and regulation.
    3. GENE THERAPY BASED ON CRISPR-CAS TECHNOLOGY: Dr. Li is at the forefront of utilizing CRISPR-Cas systems for therapeutic applications, developing strategies to correct genetic disorders and improve health outcomes.

🏆IMPACT AND INFLUENCE

  • Dr. Li’s research has significantly impacted the field of genetics, contributing to the development of novel techniques in genome editing. His work has been influential in both academic and clinical settings, paving the way for future innovations in gene therapy.

🏅ACADEMIC CITES

  • His publications have garnered a substantial number of citations, reflecting the importance and relevance of his research in the scientific community. Dr. Li’s contributions continue to inspire researchers and practitioners alike.

đź”®LEGACY AND FUTURE CONTRIBUTIONS

  • Dr. Guo Li is committed to advancing the field of genetic research and therapy. His ongoing projects aim to further refine gene editing techniques and explore new applications for CRISPR-Cas technology, ensuring a lasting legacy in molecular genetics.

đź“°PUBLICATIONS

  • Stenotrophomonas maltophilia Isolated from the Gut Symbiotic Community of the Plastic-Eating Tenebrio molitor
    Authors: Ye, S., Lu, Y., Li, G., Wu, Y., Yao, Y.
    Journal: Applied Biochemistry and Biotechnology, 2024
  •  Cellulose nanofibril matrix drives the dynamic formation of spheroids
    Authors: Lu, Y., Li, G., Li, Y., Yao, Y.
    Journal: Journal of Zhejiang University: Science B, 2023, 24(10), pp. 922–934
  •  A novel base editor SpRY-ABE8eF148A mediates efficient A-to-G base editing with a reduced off-target effect
    Authors: Li, G., Cheng, Y., Li, Y., Huang, X., Yao, Y.
    Journal: Molecular Therapy Nucleic Acids, 2023, 31, pp. 78–87
  •  Transcription-wide impact by RESCUE-induced off-Target single-nucleotide variants in mammalian cells
    Authors: Li, G., Zhu, X., Wang, Y., Yao, Y., Hu, X.
    Journal: Journal of Molecular Cell Biology, 2023, 15(2), mjad011
  •  Preventing autosomal-dominant hearing loss in Bth mice with CRISPR/CasRx-based RNA editing
    Authors: Zheng, Z., Li, G., Cui, C., Hu, X., Shu, Y.
    Journal: Signal Transduction and Targeted Therapy, 2022, 7(1), 79
Guo Li | RNA Editing | Best Researcher Award